Scientists in the United Kingdom have identified an important enzyme that helps the body produce fresh blood cells. This is an important discovery that could greatly improve stem cell therapy success rates.

Many patients receive a stem cell therapy to restore their body’s ability to create blood cells. Stem cell treatments are often used to treat cancer, metabolic disorders, immune system disorders, and metabolic disorders. The enzyme in question may greatly improve the success of these treatments.

The enzyme is called fumarase. It plays an important role in the generation of energy within cells. Researchers began to look closely at fumarase after it was revealed that it plays a role in the presence of certain blood defects in children. They discovered that children with genetic defects in the fumarase enzyme had problems with new blood cell production.

The defects caused a shortage of the fumarase enzyme. When fumarase was not produced in sufficient quantities, a molecule called fumarate would build up within the cells, causing toxic effects throughout the body.

The researcher’s findings show how enzymes like fumarase help the body’s stem cells produce new blood cells. It is another important finding that will help researchers to understand the “perfect” environment for creating new cells.

The next step will be identifying the precise biochemical pathways affected by the enzymes like fumarase. For patients requiring a stem cell therapy, these findings will help to improve their chances of having a successful treatment.

Source: Blood study insight could improve stem cell therapy success

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